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ABILIFY
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INDICATION: ABILIFY® (aripiprazole) is a prescription medicine used to treat depression in adults as an add-on treatment to an antidepressant when an antidepressant alone is not enough.

IMPORTANT WARNING ON SUICIDALITY AND ANTIDEPRESSANT DRUGS: Children, adolescents, and young adults taking antidepressants for Major Depressive Disorder (MDD) and other psychiatric disorders are at an increased risk of suicidal thinking and behavior. More

U.S. FULL PRESCRIBING INFORMATION, including Boxed WARNINGS, and Medication Guide.

IMPORTANT SAFETY INFORMATION and INDICATION for ABILIFY:
U.S. FULL PRESCRIBING INFORMATION, including Boxed WARNINGS, and Medication Guide.

Antidepressants may increase suicidal thoughts or behaviors in some children, teenagers, and young adults, especially within the first few months of treatment or when the dose is changed. Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Such symptoms should be reported to the patient's healthcare provider right away, especially if they are severe or occur suddenly. ABILIFY®(aripiprazole) is not approved for use in pediatric patients with depression. See More Safety Information

INDICATION: ABILIFY (aripiprazole) is prescribed as an add-on treatment for adults with depression when an antidepressant alone is not enough.

How ABILIFY Is Thought to Work

The exact cause of depression is still unknown, but many scientists believe that an imbalance of certain neurotransmitters (chemicals that send messages in the brain) is a major factor. Neurotransmitters that affect mood and emotion include dopamine and serotonin.

Unlike Most Antidepressants,
ABILIFY Adjusts Both Dopamine and Serotonin

To help treat your depression, your doctor may prescribe an antidepressant. Two common types are SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors). As their names suggest, SSRIs are thought to affect serotonin, while SNRIs may affect both serotonin and another neurotransmitter called norepinephrine. ABILIFY is believed to help restore the balance of dopamine as well as serotonin.

ABILIFY (aripiprazole) is prescribed as an add-on treatment for adults with depression when an antidepressant alone is not enough.

Keep in mind that the exact way ABILIFY works has not been fully determined.

About ABILIFY

How ABILIFY Is Thought to Work

The exact cause of depression is still unknown, but many scientists believe that an imbalance of certain neurotransmitters (chemicals that send messages in the brain) is a major factor. Neurotransmitters that affect mood and emotion include dopamine and serotonin.

Unlike Most Antidepressants,
ABILIFY Adjusts Both Dopamine and Serotonin

To help treat your depression, your doctor may prescribe an antidepressant. Two common types are SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors). As their names suggest, SSRIs are thought to affect serotonin, while SNRIs may affect both serotonin and another neurotransmitter called norepinephrine. ABILIFY is believed to help restore the balance of dopamine as well as serotonin.

ABILIFY (aripiprazole) is prescribed as an add-on treatment for adults with depression when an antidepressant alone is not enough.

Keep in mind that the exact way ABILIFY works has not been fully determined.

Important Safety Information

ABILIFY and medicines like it have been associated with difficulty swallowing which may lead to aspiration or choking.
See More Safety Information

Ask your doctor

What type of antidepressant am I currently taking?

See more questions

"Once I learned what ABILIFY might be able to do, I was all for it." —Roy, real ABILIFY patient

Roy is taking ABILIFY (aripiprazole) along with his antidepressant to help treat his unresolved symptoms of depression. He has volunteered to share his experience and has not been paid by the makers of ABILIFY. Individual results may vary.

A 30-Day Free Trial & Savings on Refills

By signing up for the ABILIFY Savings Card, you could save in 2 ways.* *Conditions apply. Learn more
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Starting on ABILIFY It's important to work with your doctor and take ABILIFY as directed. More

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Starting on ABILIFY  

Unresolved Symptoms of Depression?
About ABILIFY
Personal Stories
Financial Support
Important Safety Information
Kalene Video Roy Video
Kalene Still Felt Stuck
The Purpose of This Story (00:20)
  • The Purpose of This Story (01:02)
  • The Details of Kalene’s Depression (00:46)
  • Why Kalene Wasn’t Satisfied With Her Antidepressant Alone (00:49)
  • How Adding ABILIFY (aripiprazole) Made a Difference (00:55)
  • Important Safety Information (06:29)
  •  
Roy Realizes He Could Do Better
It Happened in a Heartbeat (00:21)
  • The Purpose of This Story (01:01)
  • The Details of Roy’s Depression (00:54)
  • Why Roy Wasn’t Satisfied With His Antidepressant Alone (01:03)
  • How Adding ABILIFY (aripiprazole) Made a Difference (01:10)
  • Important Safety Information (06:29)
  •